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An integrative metabolomics and transcriptomics study to identify metabolic alterations in aged skin of humans in vivo
BACKGROUND: Aging human skin undergoes significant morphological and functional changes such as wrinkle formation, reduced wound healing capacity, and altered epidermal barrier function. Besides known age-related alterations like DNA-methylation changes, metabolic adaptations have been recently link...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312537/ https://www.ncbi.nlm.nih.gov/pubmed/28201987 http://dx.doi.org/10.1186/s12864-017-3547-3 |