The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming

Metastasis is the major cause of death in cancer patients, yet the genetic and epigenetic programs that drive metastasis are poorly understood. Here, we report an epigenetic reprogramming pathway that is required for breast cancer metastasis. Concerted differential DNA methylation is initiated by th...

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Detalles Bibliográficos
Autores principales: Cunha, Stéphanie, Lin, Yi-Chun, Goossen, Elizabeth A., DeVette, Christa I., Albertella, Mark R., Thomson, Stuart, Mulvihill, Mark J., Welm, Alana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312658/
https://www.ncbi.nlm.nih.gov/pubmed/24388747
http://dx.doi.org/10.1016/j.celrep.2013.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312658/
https://www.ncbi.nlm.nih.gov/pubmed/24388747
http://dx.doi.org/10.1016/j.celrep.2013.12.010

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