Δ40p53α suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cells

Splice variants of certain genes impact on genetic biodiversity in mammals. The tumor suppressor TP53 gene (encoding p53) plays an important role in the regulation of tumorigenesis in hepatocellular carcinoma (HCC). Δ40p53α is a naturally occurring p53 isoform that lacks the N-terminal transactivati...

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Detalles Bibliográficos
Autores principales: Ota, Akinobu, Nakao, Haruhisa, Sawada, Yumi, Karnan, Sivasundaram, Wahiduzzaman, Md, Inoue, Tadahisa, Kobayashi, Yuji, Yamamoto, Takaya, Ishii, Norimitsu, Ohashi, Tomohiko, Nakade, Yukiomi, Sato, Ken, Itoh, Kiyoaki, Konishi, Hiroyuki, Hosokawa, Yoshitaka, Yoneda, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312733/
https://www.ncbi.nlm.nih.gov/pubmed/27980070
http://dx.doi.org/10.1242/jcs.190736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312733/
https://www.ncbi.nlm.nih.gov/pubmed/27980070
http://dx.doi.org/10.1242/jcs.190736

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