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Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis

Recent advances in the scale and diversity of population genomic datasets for bacteria now provide the potential for genome-wide patterns of co-evolution to be studied at the resolution of individual bases. Here we describe a new statistical method, genomeDCA, which uses recent advances in computati...

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Detalles Bibliográficos
Autores principales: Skwark, Marcin J., Croucher, Nicholas J., Puranen, Santeri, Chewapreecha, Claire, Pesonen, Maiju, Xu, Ying Ying, Turner, Paul, Harris, Simon R., Beres, Stephen B., Musser, James M., Parkhill, Julian, Bentley, Stephen D., Aurell, Erik, Corander, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312804/
https://www.ncbi.nlm.nih.gov/pubmed/28207813
http://dx.doi.org/10.1371/journal.pgen.1006508