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DNA methylation of the Fthl17 5’-upstream region regulates differential Fthl17 expression in lung cancer cells and germline stem cells

The Ferritin heavy polypeptide-like 17 (Fthl17) gene is a member of the cancer/testis antigen gene family, and is preferentially expressed in cancer cells and in testis. Although DNA methylation has been linked to the regulation of human FTHL17 gene expression, detailed epigenetic regulation of its...

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Detalles Bibliográficos
Autores principales: Aoki, Nana, Mochizuki, Kentaro, Matsui, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312872/
https://www.ncbi.nlm.nih.gov/pubmed/28207785
http://dx.doi.org/10.1371/journal.pone.0172219