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Muscle Derived Stem Cells Stimulate Muscle Myofiber Repair and Counteract Fat Infiltration in a Diabetic Mouse Model of Critical Limb Ischemia

BACKGROUND: Critical Limb Ischemia (CLI) affects patients with Type 2 Diabetes (T2D) and obesity, with high risk of amputation and post-surgical mortality, and no effective medical treatment. Stem cell therapy, mainly with bone marrow mesenchymal, adipose derived, endothelial, hematopoietic, and umb...

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Detalles Bibliográficos
Autores principales: Tsao, J, Kovanecz, I, Awadalla, N, Gelfand, R, Sinha-Hikim, I, White, RA, Gonzalez-Cadavid, NF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313052/
https://www.ncbi.nlm.nih.gov/pubmed/28217409
http://dx.doi.org/10.4172/2157-7633.1000370