An inhibitory mono-ubiquitylation of the Drosophila initiator caspase Dronc functions in both apoptotic and non-apoptotic pathways

Apoptosis is an evolutionary conserved cell death mechanism, which requires activation of initiator and effector caspases. The Drosophila initiator caspase Dronc, the ortholog of mammalian Caspase-2 and Caspase-9, has an N-terminal CARD domain that recruits Dronc into the apoptosome for activation....

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Detalles Bibliográficos
Autores principales: Kamber Kaya, Hatem Elif, Ditzel, Mark, Meier, Pascal, Bergmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313150/
https://www.ncbi.nlm.nih.gov/pubmed/28207763
http://dx.doi.org/10.1371/journal.pgen.1006438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313150/
https://www.ncbi.nlm.nih.gov/pubmed/28207763
http://dx.doi.org/10.1371/journal.pgen.1006438

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