Comparison of whole genome amplification techniques for human single cell exome sequencing

BACKGROUND: Whole genome amplification (WGA) is currently a prerequisite for single cell whole genome or exome sequencing. Depending on the method used the rate of artifact formation, allelic dropout and sequence coverage over the genome may differ significantly. RESULTS: The largest difference betw...

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Detalles Bibliográficos
Autores principales: Borgström, Erik, Paterlini, Marta, Mold, Jeff E., Frisen, Jonas, Lundeberg, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313163/
https://www.ncbi.nlm.nih.gov/pubmed/28207771
http://dx.doi.org/10.1371/journal.pone.0171566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313163/
https://www.ncbi.nlm.nih.gov/pubmed/28207771
http://dx.doi.org/10.1371/journal.pone.0171566

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