Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis

BACKGROUND: Intestinal fibrosis is characterized by abnormal production and deposition of extracellular matrix (ECM) proteins by activated myofibroblasts. The main progenitor cells of activated myofibroblasts are the fibroblasts and the epithelial cells, the latter through the epithelial-mesenchymal...

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Detalles Bibliográficos
Autores principales: Di Gregorio, Jacopo, Sferra, Roberta, Speca, Silvia, Vetuschi, Antonella, Dubuquoy, Caroline, Desreumaux, Pierre, Pompili, Simona, Cristiano, Loredana, Gaudio, Eugenio, Flati, Vincenzo, Latella, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313173/
https://www.ncbi.nlm.nih.gov/pubmed/28207769
http://dx.doi.org/10.1371/journal.pone.0171093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313173/
https://www.ncbi.nlm.nih.gov/pubmed/28207769
http://dx.doi.org/10.1371/journal.pone.0171093

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