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Protected graft copolymer-formulated fibroblast growth factors mitigate the lethality of partial body irradiation injury

We evaluated the mitigating effects of fibroblast growth factor 4 and 7 (FGF4 and FGF7, respectively) in comparison with long acting protected graft copolymer (PGC)-formulated FGF4 and 7 (PF4 and PF7, respectively) administered to C57BL/6J mice a day after exposure to LD50/30 (15.7 Gy) partial body...

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Detalles Bibliográficos
Autores principales: Castillo, Gerardo M., Nishimoto-Ashfield, Akiko, Jones, Cynthia C., Kabirov, Kasim K., Zakharov, Alexander, Lyubimov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313194/
https://www.ncbi.nlm.nih.gov/pubmed/28207794
http://dx.doi.org/10.1371/journal.pone.0171703