Skeletal muscle metabolic adaptations to endurance exercise training are attainable in mice with simvastatin treatment

We tested the hypothesis that a 6-week regimen of simvastatin would attenuate skeletal muscle adaptation to low-intensity exercise. Male C57BL/6J wildtype mice were subjected to 6-weeks of voluntary wheel running or normal cage activities with or without simvastatin treatment (20 mg/kg/d, n = 7–8 pe...

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Detalles Bibliográficos
Autores principales: Southern, William M., Nichenko, Anna S., Shill, Daniel D., Spencer, Corey C., Jenkins, Nathan T., McCully, Kevin K., Call, Jarrod A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313210/
https://www.ncbi.nlm.nih.gov/pubmed/28207880
http://dx.doi.org/10.1371/journal.pone.0172551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313210/
https://www.ncbi.nlm.nih.gov/pubmed/28207880
http://dx.doi.org/10.1371/journal.pone.0172551

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