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A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803

PURPOSE. Tumor levels of thymidylate synthase (TS), a target of 5‐fluorouracil (5‐FU)‐based chemotherapy for colorectal cancer, have been studied as a predictive or prognostic biomarker with mixed results. PATIENTS AND METHODS. Tumor TS levels were prospectively evaluated in two adjuvant therapy tri...

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Detalles Bibliográficos
Autores principales: Niedzwiecki, Donna, Hasson, Rian M., Lenz, Heinz‐Josef, Ye, Cynthia, Redston, Mark, Ogino, Shuji, Fuchs, Charles S., Compton, Carolyn C., Mayer, Robert J., Goldberg, Richard M., Colacchio, Thomas A., Saltz, Leonard B., Warren, Robert S., Bertagnolli, Monica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Blackwell 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313270/
https://www.ncbi.nlm.nih.gov/pubmed/27821793
http://dx.doi.org/10.1634/theoncologist.2016-0215