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A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803
PURPOSE. Tumor levels of thymidylate synthase (TS), a target of 5‐fluorouracil (5‐FU)‐based chemotherapy for colorectal cancer, have been studied as a predictive or prognostic biomarker with mixed results. PATIENTS AND METHODS. Tumor TS levels were prospectively evaluated in two adjuvant therapy tri...
Autores principales: | Niedzwiecki, Donna, Hasson, Rian M., Lenz, Heinz‐Josef, Ye, Cynthia, Redston, Mark, Ogino, Shuji, Fuchs, Charles S., Compton, Carolyn C., Mayer, Robert J., Goldberg, Richard M., Colacchio, Thomas A., Saltz, Leonard B., Warren, Robert S., Bertagnolli, Monica M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley-Blackwell
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313270/ https://www.ncbi.nlm.nih.gov/pubmed/27821793 http://dx.doi.org/10.1634/theoncologist.2016-0215 |
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