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Immuno-Efficacy of a T. gondii Secreted Protein with an Altered Thrombospondin Repeat (TgSPATR) As a Novel DNA Vaccine Candidate against Acute Toxoplasmosis in BALB/c Mice

Toxoplasma gondii (T.gondii) is distributed worldwide and infects most species of warm-blooded animals, including humans. Toxoplasmosis has serious consequences, especially in people with an impaired or immature immune system. Thus, an effective vaccine is urgently required. Secretory microneme prot...

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Detalles Bibliográficos
Autores principales: Zheng, Bin, Ding, Jianzu, Chen, Xiaoheng, Yu, Haijie, Lou, Di, Tong, Qunbo, Kong, Qingming, Lu, Shaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313532/
https://www.ncbi.nlm.nih.gov/pubmed/28261175
http://dx.doi.org/10.3389/fmicb.2017.00216