Development and characterization of anti‐glycopeptide monoclonal antibodies against human podoplanin, using glycan‐deficient cell lines generated by CRISPR/Cas9 and TALEN

Human podoplanin (hPDPN), which binds to C‐type lectin‐like receptor‐2 (CLEC‐2), is involved in platelet aggregation and cancer metastasis. The expression of hPDPN in cancer cells or cancer‐associated fibroblasts indicates poor prognosis. Human lymphatic endothelial cells, lung‐type I alveolar cells...

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Detalles Bibliográficos
Autores principales: Kaneko, Mika K., Nakamura, Takuro, Honma, Ryusuke, Ogasawara, Satoshi, Fujii, Yuki, Abe, Shinji, Takagi, Michiaki, Harada, Hiroyuki, Suzuki, Hiroyoshi, Nishioka, Yasuhiko, Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313638/
https://www.ncbi.nlm.nih.gov/pubmed/28101903
http://dx.doi.org/10.1002/cam4.954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313638/
https://www.ncbi.nlm.nih.gov/pubmed/28101903
http://dx.doi.org/10.1002/cam4.954

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