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Development and characterization of anti‐glycopeptide monoclonal antibodies against human podoplanin, using glycan‐deficient cell lines generated by CRISPR/Cas9 and TALEN
Human podoplanin (hPDPN), which binds to C‐type lectin‐like receptor‐2 (CLEC‐2), is involved in platelet aggregation and cancer metastasis. The expression of hPDPN in cancer cells or cancer‐associated fibroblasts indicates poor prognosis. Human lymphatic endothelial cells, lung‐type I alveolar cells...
Autores principales: | Kaneko, Mika K., Nakamura, Takuro, Honma, Ryusuke, Ogasawara, Satoshi, Fujii, Yuki, Abe, Shinji, Takagi, Michiaki, Harada, Hiroyuki, Suzuki, Hiroyoshi, Nishioka, Yasuhiko, Kato, Yukinari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313638/ https://www.ncbi.nlm.nih.gov/pubmed/28101903 http://dx.doi.org/10.1002/cam4.954 |
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