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Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen

Urocortin (UCN1) peptide shares structural and functional homology with corticotropin‐releasing factor (CRF). UCN1 is significantly reduced in endometrial adenocarcinoma compared to healthy controls. However, there are no data which evaluate the effects of UCN1 in the endometrium, or how it is modul...

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Detalles Bibliográficos
Autores principales: Owens, Gemma L., Lawrence, Kevin M., Jackson, Tom R., Crosbie, Emma J., Sayan, Berna S., Kitchener, Henry C., Townsend, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313640/
https://www.ncbi.nlm.nih.gov/pubmed/28109061
http://dx.doi.org/10.1002/cam4.967