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Up‐regulation of miR‐497 confers resistance to temozolomide in human glioma cells by targeting mTOR/Bcl‐2

The occurrence of an inherent or acquired resistance to temozolomide (TMZ) is a major burden for patients suffering from glioma. Recently, studies have demonstrated that microRNAs play an important role in the regulation of tumor properties in cancers. However, whether miR‐497 contributes to glioma...

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Detalles Bibliográficos
Autores principales: Zhu, Danhua, Tu, Ming, Zeng, Bo, Cai, Lin, Zheng, Weiming, Su, Zhipeng, Yu, Zhengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313645/
https://www.ncbi.nlm.nih.gov/pubmed/28064447
http://dx.doi.org/10.1002/cam4.987