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Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks

Replication is not as continuous as once thought, with DNA damage frequently stalling replication forks. Aberrant repair of stressed replication forks can result in cell death or genome instability and resulting transformation to malignancy. Stressed replication forks are most commonly repaired via...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Suk, Nickoloff, Jac A., Wu, Yuehan, Williamson, Elizabeth A., Sidhu, Gurjit Singh, Reinert, Brian L., Jaiswal, Aruna S., Srinivasan, Gayathri, Patel, Bhavita, Kong, Kimi, Burma, Sandeep, Lee, Suk-Hee, Hromas, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314175/
https://www.ncbi.nlm.nih.gov/pubmed/28049724
http://dx.doi.org/10.1074/jbc.M116.758235