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Epigenetic and genetic dissections of UV-induced global gene dysregulation in skin cells through multi-omics analyses

To elucidate the complex molecular mechanisms underlying the adverse effects UV radiation (UVR) on skin homeostasis, we performed multi-omics studies to characterize UV-induced genetic and epigenetic changes. Human keratinocytes from a single donor treated with or without UVR were analyzed by RNA-se...

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Detalles Bibliográficos
Autores principales: Shen, Yao, Stanislauskas, Milda, Li, Gen, Zheng, Deyou, Liu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314319/
https://www.ncbi.nlm.nih.gov/pubmed/28211524
http://dx.doi.org/10.1038/srep42646