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Epigenetic and genetic dissections of UV-induced global gene dysregulation in skin cells through multi-omics analyses
To elucidate the complex molecular mechanisms underlying the adverse effects UV radiation (UVR) on skin homeostasis, we performed multi-omics studies to characterize UV-induced genetic and epigenetic changes. Human keratinocytes from a single donor treated with or without UVR were analyzed by RNA-se...
Autores principales: | Shen, Yao, Stanislauskas, Milda, Li, Gen, Zheng, Deyou, Liu, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314319/ https://www.ncbi.nlm.nih.gov/pubmed/28211524 http://dx.doi.org/10.1038/srep42646 |
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