The inflammatory cytokine TNF-α promotes the premature senescence of rat nucleus pulposus cells via the PI3K/Akt signaling pathway

Premature senescence of nucleus pulposus (NP) cells and inflammation are two common features of degenerated discs. This study investigated the effects of the inflammatory cytokine TNF-α on the premature senescence of NP cells and the molecular mechanism behind this process. Rat NP cells were culture...

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Detalles Bibliográficos
Autores principales: Li, Pei, Gan, Yibo, Xu, Yuan, Song, Lei, Wang, Liyuan, Ouyang, Bin, Zhang, Chengmin, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314336/
https://www.ncbi.nlm.nih.gov/pubmed/28211497
http://dx.doi.org/10.1038/srep42938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314336/
https://www.ncbi.nlm.nih.gov/pubmed/28211497
http://dx.doi.org/10.1038/srep42938

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