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The inflammatory cytokine TNF-α promotes the premature senescence of rat nucleus pulposus cells via the PI3K/Akt signaling pathway

Premature senescence of nucleus pulposus (NP) cells and inflammation are two common features of degenerated discs. This study investigated the effects of the inflammatory cytokine TNF-α on the premature senescence of NP cells and the molecular mechanism behind this process. Rat NP cells were culture...

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Detalles Bibliográficos
Autores principales:	Li, Pei, Gan, Yibo, Xu, Yuan, Song, Lei, Wang, Liyuan, Ouyang, Bin, Zhang, Chengmin, Zhou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314336/ https://www.ncbi.nlm.nih.gov/pubmed/28211497 http://dx.doi.org/10.1038/srep42938

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