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Molecular Basis of ABHD5 Lipolysis Activation

Alpha-beta hydrolase domain-containing 5 (ABHD5), the defective gene in human Chanarin-Dorfman syndrome, is a highly conserved regulator of adipose triglyceride lipase (ATGL)-mediated lipolysis that plays important roles in metabolism, tumor progression, viral replication, and skin barrier formation...

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Detalles Bibliográficos
Autores principales: Sanders, Matthew A., Zhang, Huamei, Mladenovic, Ljiljana, Tseng, Yan Yuan, Granneman, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314347/
https://www.ncbi.nlm.nih.gov/pubmed/28211464
http://dx.doi.org/10.1038/srep42589