PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy

Macrophages have been demonstrated to play a proangiogenic role in retinal pathological vascular growth. Pigment epithelium-derived factor (PEDF) works as a powerful endogenous angiogenesis inhibitor, but its role in macrophage recruitment and polarization is largely unknown. To explore the underlyi...

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Detalles Bibliográficos
Autores principales: Gao, Sha, Li, Changwei, Zhu, Yanji, Wang, Yanuo, Sui, Ailing, Zhong, Yisheng, Xie, Bing, Shen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314378/
https://www.ncbi.nlm.nih.gov/pubmed/28211523
http://dx.doi.org/10.1038/srep42846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314378/
https://www.ncbi.nlm.nih.gov/pubmed/28211523
http://dx.doi.org/10.1038/srep42846

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