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PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy

Macrophages have been demonstrated to play a proangiogenic role in retinal pathological vascular growth. Pigment epithelium-derived factor (PEDF) works as a powerful endogenous angiogenesis inhibitor, but its role in macrophage recruitment and polarization is largely unknown. To explore the underlyi...

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Detalles Bibliográficos
Autores principales:	Gao, Sha, Li, Changwei, Zhu, Yanji, Wang, Yanuo, Sui, Ailing, Zhong, Yisheng, Xie, Bing, Shen, Xi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314378/ https://www.ncbi.nlm.nih.gov/pubmed/28211523 http://dx.doi.org/10.1038/srep42846

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