Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism

Hepatocytes release extracellular vesicles (EVs) loaded with signaling molecules and enzymes into the bloodstream. Although the importance of EVs in the intercellular communication is already recognized, the metabolic impact of the enzymes carried by these vesicles is still unclear. We evaluated the...

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Detalles Bibliográficos
Autores principales: Royo, Felix, Moreno, Laura, Mleczko, Justyna, Palomo, Laura, Gonzalez, Esperanza, Cabrera, Diana, Cogolludo, Angel, Vizcaino, Francisco Perez, van-Liempd, Sebastiaan, Falcon-Perez, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314384/
https://www.ncbi.nlm.nih.gov/pubmed/28211494
http://dx.doi.org/10.1038/srep42798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314384/
https://www.ncbi.nlm.nih.gov/pubmed/28211494
http://dx.doi.org/10.1038/srep42798

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