Regulation of mRNA splicing by MeCP2 via epigenetic modifications in the brain

Mutations of X-linked gene Methyl CpG binding protein 2 (MECP2) are the major causes of Rett syndrome (RTT), a severe neurodevelopmental disorder. Duplications of MECP2-containing genomic segments lead to severe autistic symptoms in human. MECP2-coding protein methyl-CpG-binding protein 2 (MeCP2) is...

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Detalles Bibliográficos
Autores principales: Cheng, Tian-Lin, Chen, Jingqi, Wan, Huida, Tang, Bin, Tian, Weidong, Liao, Lujian, Qiu, Zilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314398/
https://www.ncbi.nlm.nih.gov/pubmed/28211484
http://dx.doi.org/10.1038/srep42790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314398/
https://www.ncbi.nlm.nih.gov/pubmed/28211484
http://dx.doi.org/10.1038/srep42790

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