Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer’s Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry

[Image: see text] The major pathological hallmarks of Alzheimer’s disease (AD) are the progressive aggregation and accumulation of beta-amyloid (Aβ) and hyperphosphorylated tau protein into neurotoxic deposits. Aβ aggregation has been suggested as the critical early inducer, driving the disease prog...

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Detalles Bibliográficos
Autores principales: Kaya, Ibrahim, Brinet, Dimitri, Michno, Wojciech, Syvänen, Stina, Sehlin, Dag, Zetterberg, Henrik, Blennow, Kaj, Hanrieder, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314428/
https://www.ncbi.nlm.nih.gov/pubmed/27984697
http://dx.doi.org/10.1021/acschemneuro.6b00391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314428/
https://www.ncbi.nlm.nih.gov/pubmed/27984697
http://dx.doi.org/10.1021/acschemneuro.6b00391

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