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Tumor-Initiating Cells: a criTICal review of isolation approaches and new challenges in targeting strategies
Most cancers contain a subpopulation of highly tumorigenic cells, known as cancer stem cells (CSCs) or tumor-initiating cells (TICs). Targeting TICs may be essential to achieve cure, because of their self-renewal and tumorigenic properties as well as their resistance to conventional therapies. Despi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314476/ https://www.ncbi.nlm.nih.gov/pubmed/28209178 http://dx.doi.org/10.1186/s12943-017-0602-2 |