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Mouse genomic screen reveals novel host regulator of metastasis

Tumor cells have to overcome challenges in the host tissue microenvironment to metastasize successfully to distant organs. In a recent Nature study, a genome-wide functional screen demonstrated that deficiency of the sphingosine-1-phoshate (S1P) transporter gene Spns2 in endothelium increased immune...

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Detalles Bibliográficos
Autores principales: Celià-Terrassa, Toni, Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314612/
https://www.ncbi.nlm.nih.gov/pubmed/28209174
http://dx.doi.org/10.1186/s13059-017-1170-x