Cargando…

CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes

Diabetic nephropathy (DN) is the major cause of end-stage renal disease worldwide. Podocytes are important for glomerular filtration barrier function and maintenance of size selectivity in protein filtration in the kidney. Podocyte damage is the basis of many glomerular diseases characterized by los...

Descripción completa

Detalles Bibliográficos
Autores principales: Teng, Beina, Schroder, Patricia, Müller-Deile, Janina, Schenk, Heiko, Staggs, Lynne, Tossidou, Irini, Dikic, Ivan, Haller, Hermann, Schiffer, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314701/
https://www.ncbi.nlm.nih.gov/pubmed/27531950
http://dx.doi.org/10.2337/db16-0081