Gene regulatory network underlying the immortalization of epithelial cells

BACKGROUND: Tumorigenic transformation of human epithelial cells in vitro has been described experimentally as the potential result of spontaneous immortalization. This process is characterized by a series of cell–state transitions, in which normal epithelial cells acquire first a senescent state wh...

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Detalles Bibliográficos
Autores principales: Méndez-López, Luis Fernando, Davila-Velderrain, Jose, Domínguez-Hüttinger, Elisa, Enríquez-Olguín, Christian, Martínez-García, Juan Carlos, Alvarez-Buylla, Elena R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314717/
https://www.ncbi.nlm.nih.gov/pubmed/28209158
http://dx.doi.org/10.1186/s12918-017-0393-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314717/
https://www.ncbi.nlm.nih.gov/pubmed/28209158
http://dx.doi.org/10.1186/s12918-017-0393-5

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