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Gene regulatory network underlying the immortalization of epithelial cells

BACKGROUND: Tumorigenic transformation of human epithelial cells in vitro has been described experimentally as the potential result of spontaneous immortalization. This process is characterized by a series of cell–state transitions, in which normal epithelial cells acquire first a senescent state wh...

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Detalles Bibliográficos
Autores principales:	Méndez-López, Luis Fernando, Davila-Velderrain, Jose, Domínguez-Hüttinger, Elisa, Enríquez-Olguín, Christian, Martínez-García, Juan Carlos, Alvarez-Buylla, Elena R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314717/ https://www.ncbi.nlm.nih.gov/pubmed/28209158 http://dx.doi.org/10.1186/s12918-017-0393-5

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