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Prediction of human miRNA target genes using computationally reconstructed ancestral mammalian sequences

MicroRNAs (miRNA) are short single-stranded RNA molecules derived from hairpin-forming precursors that play a crucial role as post-transcriptional regulators in eukaryotes and viruses. In the past years, many microRNA target genes (MTGs) have been identified experimentally. However, because of the h...

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Detalles Bibliográficos
Autores principales: Leclercq, Mickael, Diallo, Abdoulaye Baniré, Blanchette, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314757/
https://www.ncbi.nlm.nih.gov/pubmed/27899600
http://dx.doi.org/10.1093/nar/gkw1085