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Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases

Current models of bacterial homologous recombination (HR) posit that extensive resection of a DNA double-strand break (DSB) by a multisubunit helicase–nuclease machine (e.g. RecBCD, AddAB or AdnAB) generates the requisite 3′ single-strand DNA substrate for RecA-mediated strand invasion. AdnAB, the h...

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Detalles Bibliográficos
Autores principales: Gupta, Richa, Unciuleac, Mihaela-Carmen, Shuman, Stewart, Glickman, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314763/
https://www.ncbi.nlm.nih.gov/pubmed/27899634
http://dx.doi.org/10.1093/nar/gkw1130