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Elasticity of the transition state for oligonucleotide hybridization

Despite its fundamental importance in cellular processes and abundant use in biotechnology, we lack a detailed understanding of the kinetics of nucleic acid hybridization. In particular, the identity of the transition state, which determines the kinetics of the two-state reaction, remains poorly cha...

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Detalles Bibliográficos
Autores principales: Whitley, Kevin D., Comstock, Matthew J., Chemla, Yann R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314771/
https://www.ncbi.nlm.nih.gov/pubmed/27903889
http://dx.doi.org/10.1093/nar/gkw1173