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Mg(2+) ions: do they bind to nucleobase nitrogens?

Given the many roles proposed for Mg(2+) in nucleic acids, it is essential to accurately determine their binding modes. Here, we surveyed the PDB to classify Mg(2+) inner-sphere binding patterns to nucleobase imine N1/N3/N7 atoms. Among those, purine N7 atoms are considered to be the best nucleobase...

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Detalles Bibliográficos
Autores principales: Leonarski, Filip, D'Ascenzo, Luigi, Auffinger, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314772/
https://www.ncbi.nlm.nih.gov/pubmed/27923930
http://dx.doi.org/10.1093/nar/gkw1175