Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7

The KEOPS/EKC complex is a tRNA modification complex involved in the biosynthesis of N(6)-threonylcarbamoyladenosine (t(6)A), a universally conserved tRNA modification found on ANN-codon recognizing tRNAs. In archaea and eukaryotes, KEOPS is composed of OSGEP/Kae1, PRPK/Bud32, TPRKB/Cgi121 and LAGE3...

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Detalles Bibliográficos
Autores principales: Wan, Leo C.K., Maisonneuve, Pierre, Szilard, Rachel K., Lambert, Jean-Philippe, Ng, Timothy F., Manczyk, Noah, Huang, Hao, Laister, Rob, Caudy, Amy A., Gingras, Anne-Claude, Durocher, Daniel, Sicheri, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314774/
https://www.ncbi.nlm.nih.gov/pubmed/27903914
http://dx.doi.org/10.1093/nar/gkw1181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314774/
https://www.ncbi.nlm.nih.gov/pubmed/27903914
http://dx.doi.org/10.1093/nar/gkw1181

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