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Insights into the mechanisms of eukaryotic translation gained with ribosome profiling

The development of Ribosome Profiling (RiboSeq) has revolutionized functional genomics. RiboSeq is based on capturing and sequencing of the mRNA fragments enclosed within the translating ribosome and it thereby provides a ‘snapshot’ of ribosome positions at the transcriptome wide level. Although the...

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Detalles Bibliográficos
Autores principales: Andreev, Dmitry E., O'Connor, Patrick B. F., Loughran, Gary, Dmitriev, Sergey E., Baranov, Pavel V., Shatsky, Ivan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314775/
https://www.ncbi.nlm.nih.gov/pubmed/27923997
http://dx.doi.org/10.1093/nar/gkw1190