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Molecular basis for the autonomous promotion of cell proliferation by angiogenin

Canonical growth factors act indirectly via receptor-mediated signal transduction pathways. Here, we report on an autonomous pathway in which a growth factor is internalized, has its localization regulated by phosphorylation, and ultimately uses intrinsic catalytic activity to effect epigenetic chan...

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Detalles Bibliográficos
Autores principales: Hoang, Trish T., Raines, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314776/
https://www.ncbi.nlm.nih.gov/pubmed/27915233
http://dx.doi.org/10.1093/nar/gkw1192