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Oxidative stress controls the choice of alternative last exons via a Brahma–BRCA1–CstF pathway

Alternative splicing of terminal exons increases transcript and protein diversity. How physiological and pathological stimuli regulate the choice between alternative terminal exons is, however, largely unknown. Here, we show that Brahma (BRM), the ATPase subunit of the hSWI/SNF chromatin-remodeling...

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Detalles Bibliográficos
Autores principales: Fontana, Gabriele A., Rigamonti, Aurora, Lenzken, Silvia C., Filosa, Giuseppe, Alvarez, Reinaldo, Calogero, Raffaele, Bianchi, Marco E., Barabino, Silvia M.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314785/
https://www.ncbi.nlm.nih.gov/pubmed/27591253
http://dx.doi.org/10.1093/nar/gkw780