DNA-linked Inhibitor Antibody Assay (DIANA) for sensitive and selective enzyme detection and inhibitor screening

Human diseases are often diagnosed by determining levels of relevant enzymes and treated by enzyme inhibitors. We describe an assay suitable for both ultrasensitive enzyme quantification and quantitative inhibitor screening with unpurified enzymes. In the DNA-linked Inhibitor ANtibody Assay (DIANA),...

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Detalles Bibliográficos
Autores principales: Navrátil, Václav, Schimer, Jiří, Tykvart, Jan, Knedlík, Tomáš, Vik, Viktor, Majer, Pavel, Konvalinka, Jan, Šácha, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314793/
https://www.ncbi.nlm.nih.gov/pubmed/27679479
http://dx.doi.org/10.1093/nar/gkw853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314793/
https://www.ncbi.nlm.nih.gov/pubmed/27679479
http://dx.doi.org/10.1093/nar/gkw853

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