The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing

Homologous recombination (HR) is a template-driven repair pathway that mends DNA double-stranded breaks (DSBs), and thus helps to maintain genome stability. The RAD51 recombinase facilitates DNA joint formation during HR, but to accomplish this task, RAD51 must be loaded onto the single-stranded DNA...

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Detalles Bibliográficos
Autores principales: Kelso, Andrew A., Goodson, Steven D., Watts, Leah E., Ledford, LeAnna L., Waldvogel, Sarah M., Diehl, J. Nathaniel, Shah, Shivani B., Say, Amanda F., White, Julie D., Sehorn, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314795/
https://www.ncbi.nlm.nih.gov/pubmed/27694622
http://dx.doi.org/10.1093/nar/gkw877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314795/
https://www.ncbi.nlm.nih.gov/pubmed/27694622
http://dx.doi.org/10.1093/nar/gkw877

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