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Deciphering the mechanisms of binding induced folding at nearly atomic resolution: The Φ value analysis applied to IDPs
The Φ value analysis is a method to analyze the structure of metastable states in reaction pathways. Such a methodology is based on the quantitative analysis of the effect of point mutations on the kinetics and thermodynamics of the probed reaction. The Φ value analysis is routinely used in protein...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314873/ https://www.ncbi.nlm.nih.gov/pubmed/28232881 http://dx.doi.org/10.4161/idp.28624 |