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Effect of interleukin (IL)-35 on IL-17 expression and production by human CD4(+) T cells

BACKGROUND: Interleukin (IL)-17 produced by mainly T helper 17 (Th17) cells may play an important destructive role in chronic periodontitis (CP). Thus, anti-inflammatory cytokines, such as IL-35, might have a beneficial effect in periodontitis by inhibiting differentiation of Th17 cells. Th17 differ...

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Detalles Bibliográficos
Autores principales: Okada, Kosuke, Fujimura, Takeki, Kikuchi, Takeshi, Aino, Makoto, Kamiya, Yosuke, Izawa, Ario, Iwamura, Yuki, Goto, Hisashi, Okabe, Iichiro, Miyake, Eriko, Hasegawa, Yoshiaki, Mogi, Makio, Mitani, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314955/
https://www.ncbi.nlm.nih.gov/pubmed/28229025
http://dx.doi.org/10.7717/peerj.2999