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Impact of Tigecycline Versus Other Antibiotics on the Fecal Metabolome and on Colonization Resistance to Clostridium difficile in Mice

BACKGROUND: The glycylcycline antibiotic tigecycline may have a relatively low propensity to promote Clostridium difficile infection in part because it causes less disruption of the indigenous intestinal microbiota than other broad-spectrum antibiotics. We used a mouse model to compare the effects o...

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Detalles Bibliográficos
Autores principales: Jump, Robin L.P., Kraft, David, Hurless, Kelly, Polinkovsky, Alex, Donskey, Curtis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pathogens and Immunity 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315001/
https://www.ncbi.nlm.nih.gov/pubmed/28217763
http://dx.doi.org/10.20411/pai.v2i1.159