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Impact of Tigecycline Versus Other Antibiotics on the Fecal Metabolome and on Colonization Resistance to Clostridium difficile in Mice

BACKGROUND: The glycylcycline antibiotic tigecycline may have a relatively low propensity to promote Clostridium difficile infection in part because it causes less disruption of the indigenous intestinal microbiota than other broad-spectrum antibiotics. We used a mouse model to compare the effects o...

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Detalles Bibliográficos
Autores principales:	Jump, Robin L.P., Kraft, David, Hurless, Kelly, Polinkovsky, Alex, Donskey, Curtis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pathogens and Immunity 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315001/ https://www.ncbi.nlm.nih.gov/pubmed/28217763 http://dx.doi.org/10.20411/pai.v2i1.159

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