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Altered fronto-striatal functions in the Gdi1-null mouse model of X-linked Intellectual Disability

RAB-GDP dissociation inhibitor 1 (GDI1) loss-of-function mutations are responsible for a form of non-specific X-linked Intellectual Disability (XLID) where the only clinical feature is cognitive impairment. GDI1 patients are impaired in specific aspects of executive functions and conditioned respons...

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Detalles Bibliográficos
Autores principales: Morè, Lorenzo, Künnecke, Basil, Yekhlef, Latefa, Bruns, Andreas, Marte, Antonella, Fedele, Ernesto, Bianchi, Veronica, Taverna, Stefano, Gatti, Silvia, D'Adamo, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315088/
https://www.ncbi.nlm.nih.gov/pubmed/28057534
http://dx.doi.org/10.1016/j.neuroscience.2016.12.043