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Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival

Increased β-cell death coupled with the inability to replicate existing β-cells drives the decline in β-cell mass observed in the progression of both major forms of diabetes. Understanding endogenous mechanisms of islet cell survival could have considerable value for the development of novel strateg...

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Detalles Bibliográficos
Autores principales: Hayes, Heather L., Peterson, Brett S., Haldeman, Jonathan M., Newgard, Christopher B., Hohmeier, Hans E., Stephens, Samuel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315295/
https://www.ncbi.nlm.nih.gov/pubmed/28212395
http://dx.doi.org/10.1371/journal.pone.0172567